United States - English - NLM (National Library of Medicine)

akorn - methylergonovine maleate (unii: ir84jpz1rk) (methylergonovine - unii:w53l6fe61v) - following delivery of the placenta, for routine management of uterine atony, hemorrhage and subinvolution of the uterus. for control of uterine hemorrhage in the second stage of labor following delivery of the anterior shoulder. hypertension; toxemia; pregnancy; and hypersensitivity. methylergonovine maleate has not been associated with drug abuse or dependence of either a physical or psychological nature.

United States - English - NLM (National Library of Medicine)

akorn, inc. - hyaluronidase (unii: 8kog53z5em) (hyaluronidase - unii:8kog53z5em) - hydase™ (hyaluronidase injection) is indicated as an adjuvant to increase the absorption and dispersion of other injected drugs. hydase™ is indicated as an adjuvant in subcutaneous fluid administration for achieving hydration. hydase™ is indicated as an adjuvant in subcutaneous urography for improving resorption of radiopaque. hydase™ contraindicated in patients with known hypersensitivity to hyaluronidase or any other ingredient in the formulation. a preliminary skin test for hypersensitivity to hydase™ can be performed. the skin test is made by an intradermal injection of approximately 0.02 ml (3 units) of a 150 unit/ml solution [see dosage and administration (2) ]. a positive reaction consists of a wheal with pseudopods appearing within five minutes and persisting for 20 to 30 minutes and accompanied by localized itching. transient vasodilation at the site of the test, i.e., erythema, is not a positive reaction. discontinue hydase™ if sensitization occurs. no adequate and well controlled animal studi

United States - English - NLM (National Library of Medicine)

akorn - sodium chloride (unii: 451w47iq8x) (chloride ion - unii:q32zn48698, sodium cation - unii:lyr4m0nh37), potassium chloride (unii: 660yq98i10) (potassium cation - unii:295o53k152, chloride ion - unii:q32zn48698), calcium chloride (unii: m4i0d6vv5m) (calcium cation - unii:2m83c4r6zb, chloride ion - unii:q32zn48698), magnesium chloride (unii: 02f3473h9o) (magnesium cation - unii:t6v3lhy838, chloride ion - unii:q32zn48698), sodium acetate (unii: 4550k0sc9b) (acetate ion - unii:569dqm74sc, sodium cation - uni - for use as an extraocular and intraocular irrigating solution during ocular surgical procedure involving perfusion of the eye with an expected maximum duration of less than 60 minutes.

United States - English - NLM (National Library of Medicine)

akorn - cyclopentolate hydrochloride (unii: 736i6971te) (cyclopentolate - unii:i76f4shp7j) - cyclopentolate hydrochloride ophthalmic solution is used to produce mydriasis and cycloplegia. cyclopentolate hydrochloride ophthalmic solution should not be used when untreated narrow-angle glaucoma, or untreated anatomically narrow angles are present, or if the patient is hypersensitive to any component of this preparation.

United States - English - NLM (National Library of Medicine)

akorn - lactulose (unii: 9u7d5qh5ae) (lactulose - unii:9u7d5qh5ae) - for the treatment of constipation. in patients with a history of chronic constipation, lactulose solution therapy increases the number of bowel movements per day and the number of days on which bowel movements occur. since lactulose solution contains galactose (less than 1.6 g/15 ml), it is contraindicated in patients who require a low galactose diet.

United States - English - NLM (National Library of Medicine)

akorn - gentamicin sulfate (unii: 8x7386qrlv) (gentamicin - unii:t6z9v48ikg) - gentamicin sulfate sterile ophthalmic solution is indicated in the topical treatment of ocular bacterial infections, including conjunctivitis, keratitis, keratoconjunctivitis, corneal ulcers, blepharitis, blepharoconjunctivitis, acute meibomianitis, and dacryocystitis caused by susceptible strains of the following microorganisms: gentamicin sulfate sterile ophthalmic solution is contraindicated in patients with known hypersensitivity to any of the components.

United States - English - NLM (National Library of Medicine)

akorn - orphenadrine citrate (unii: x0a40n8i4s) (orphenadrine - unii:al805o9og9) - orphenadrine citrate injection is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions. the mode of action of the drug has not been clearly identified, but may be related to its analgesic properties. orphenadrine citrate does not directly relax tense skeletal muscles in man. contraindicated in patients with glaucoma, pyloric or duodenal obstruction, stenosing peptic ulcers, prostatic hypertrophy or obstruction of the bladder neck, cardio-spasm (megaesophagus) and myasthenia gravis. contraindicated in patients who have demonstrated a previous hypersensitivity to the drug. orphenadrine has been chronically abused for its euphoric effects. the mood elevating effects may occur at therapeutic doses of orphenadrine.

United States - English - NLM (National Library of Medicine)

akorn, inc. - bacitracin a (unii: dda3rrx0p7) (bacitracin a - unii:dda3rrx0p7) - in accordance with the statements in the "warning box", the use of intramuscular bacitracin for injection, usp is limited to the treatment of infants with pneumonia and empyema caused by staphylococci shown to be susceptible to the drug. to reduce the development of drug-resistant bacteria and maintain the effectiveness of bacitracin for injection, usp and other antibacterial drugs, bacitracin for injection, usp should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. when culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. in the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. this drug is contraindicated in those individuals with a history of previous hypersensitivity or toxic reaction to it.

United States - English - NLM (National Library of Medicine)

akorn - calcitriol (unii: fxc9231jvh) (calcitriol - unii:fxc9231jvh) - calcitriol injection is indicated in the management of hypocalcemia in patients undergoing chronic renal dialysis. it has been shown to significantly reduce elevated parathyroid hormone levels. reduction of pth has been shown to result in an improvement in renal osteodystrophy. calcitriol injection should not be given to patients with hypercalcemia or evidence of vitamin d toxicity. calcitriol injection is contraindicated in patients with previous hypersensitivity to calcitriol or any of its excipients.

United States - English - NLM (National Library of Medicine)

akorn - chlorothiazide sodium (unii: sn86fg7n2k) (chlorothiazide - unii:77w477j15h) - chlorothiazide sodium for injection is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. chlorothiazide sodium for injection has also been found useful in edema due to various forms of renal dysfunction such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure. routine use of diuretics during normal pregnancy is inappropriate and exposes mother and fetus to unnecessary hazard. diuretics do not prevent development of toxemia of pregnancy and there is no satisfactory evidence that they are useful in the treatment of toxemia. edema during pregnancy may arise from pathologic causes or from the physiologic and mechanical consequences of pregnancy. thiazides are indicated in pregnancy when edema is due to pathologic causes, just as they are in the absence of pregnancy (see precautions, pregnancy). dependent edema in pregnancy, resulting from restriction of venous return by the gravid uterus, is properl